Arquivos Brasileiros de Oftalmologia - DRESS syndrome in

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially fatal adverse drug reaction associated with skin rash, fever, eosinophilia, and multiple organ injury. A number of pharmacological agents are known to cause DRESS syndrome such as allopurinol, anticonvulsants, vancomycin, trimethoprime-sulfamethoxazole, and pyrimethamine-sulfadiazine. Here, we describe two patients who developed DRESS syndrome during ocular treatment. The first case was being treated for late postoperative endophthalmitis with topical antibiotics, intravenous cephalothin, meropenem, and intravitreal injection of vancomycin and ceftazidime before symptoms developed. We were unable to identify the causal drug owing to the large number of medications concurrently administered. The second case presented with DRESS syndrome symptoms during ocular toxoplasmosis treatment. In this case, a clearer association with pyrimethamine-sulfadiazine was observed. As a result of the regular prescription of pharmacological agents associated with DRESS syndrome, ophthalmologists should be aware of the potentially serious complications of DRESS syndrome.

Michael Wormstone — University of Nottingham Ningbo China

54-85-3, MFCD00006426, Isoniazid

Dr. Arthur Frazão - Tua Saúde

Figure 7 from [DRESS syndrome].

Figure 7 from [DRESS syndrome].

Enrico BORRELLI, Associate Professor of Ophthalmology, MD, PhD, FEBO, Università degli Studi di Torino, Turin, UNITO, Department of Surgical Sciences

PDF) Análise ultraestrutural e de fatores de crescimento de diferentes métodos de preservação da membrana amniótica utilizada em cirurgia ocular

Arquivos de Asma, Alergia e Imunologia - AAAI

Arquivos Brasileiros de Oftalmologia - Summary

REVISTA SBCCP 40 1 completa - Centro Cirúrgico