Kyle Bradley, MD on X: Megaloblastic neutrophils in bone marrow
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Kyle Bradley, MD on X: These are indeed plasma cells. Plasma cells can sometimes be multinucleated and even resemble megakaryocytes! A CD138 IHC stain is shown. Also, see this post (different case)
Selected Abstracts from the 12th Annual Meeting of the Clinical Immunology Society: 2021 Virtual Annual Meeting: Immune Deficiency and Dysregulation North American Conference
Haematologica, volume 101, issue 10 by Haematologica - Issuu
100 Cases Study
Kyle Bradley, MD on X: Plasma cells can sometimes resemble megakaryocytes! One key differentiating feature: the two giant plasma cells have agranular cytoplasm. Compare to the megakaryocyte (inset). Bone marrow aspirate smear
PDF) cap.org 2012 Hematology, Clinical Microscopy, and Body Fluids Glossary
Kyle Bradley, MD on X: Tips for determining bone marrow % cellularity: Step 1) More cells, more fat, or about equal? Step 2) Estimate % cellularity AND % fatularity (I made up
Williams Hematology-McGraw-Hill (2015).pdf
Hematopathology Resident / Fellow Manual - Department of
Kyle Bradley, MD on X: Essential thrombocythemia. Classic large megakaryocytes with abundant cytoplasm and hyperlobulated (staghorn) nuclei. Plt = 935 k/uL. / X