Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer

Cryo-EM structures of the HER2-HER3-NRG1b receptor complex reveal

CIMB, Free Full-Text

Pathogenic HER3 dimerization domain mutations create a structural

A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor

In-depth structural and functional analysis of the NRG1β binding

Her2 activation mechanism reflects evolutionary preservation of

A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor

Cryo-EM analyses of wild-type and oncogenic KIT mutants reveal structural oncogenic plasticity and a novel “Achilles heel” for therapeutic intervention

Biomolecules, Free Full-Text