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Guillain-Barré and Alpha-gal Syndromes: Saccharides-induced Immune Responses

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The molecular interactions between hosts, vectors and pathogens drive the etiology of infectious diseases. At first sight, the Guillain-Barré and Alpha-Gal syndromes have quite different etiologies but, as proposed here, a closer look into the immune response to galactose-containing oligosaccharide structures that characterizes these two diseases reveals striking commonalities. In this Opinion paper, we address the main molecular drivers of two apparently unrelated diseases, and how the characterization of the immune response and immunological tolerance would advance the control and prevention of these diseases.

Jose DE LA FUENTE, Professor (Full), PhD, University of Castilla-La Mancha, Ciudad Real, Sanidad y Biotecnología (SaBio)

Guillain-Barré syndrome - The Lancet

PDF) Guillain-Barré and Alpha-gal Syndromes: Saccharides-induced Immune Responses

Alejandro CABEZAS-CRUZ, Principal Investigator, Doctor of Philosophy (PhD), French National Institute for Agriculture, Food, and Environment (INRAE), Paris, INRAE, Department of Animal Health

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Alejandro CABEZAS-CRUZ, Principal Investigator, Doctor of Philosophy (PhD), French National Institute for Agriculture, Food, and Environment (INRAE), Paris, INRAE, Department of Animal Health

Guillain-Barré syndrome: expanding the concept of molecular mimicry - ScienceDirect

IBC - 最新發表論文

Jose DE LA FUENTE, Professor (Full), PhD, University of Castilla-La Mancha, Ciudad Real, Sanidad y Biotecnología (SaBio)

PDF) Guillain-Barré and Alpha-gal Syndromes: Saccharides-induced Immune Responses

GB - Sx de Guillian-Barre - Guillain-Barré Syndrome By Ali A. Habib, MD; Waqar Waheed, MD ABSTRACT - Studocu